Rheumatic fever and HLA antigens
Medicina (Ribeiräo Preto)
;
33(1): 55-59, jan.-mar. 2000. tab
Artigo
em Inglês
| LILACS
| ID: lil-331504
ABSTRACT
In this study we typed HLA class I and II antigens in a series of patients presenting with the distinct major clinical manifestations of rheumatic fever (RF), i.e, chorea, carditis or arthritis. Ninety-one patients with RF were evaluated for HLA-A, -B and -DR antigens. Thirty-three had pure chorea, 26 pure carditis, 16 pure arthritis, and 16 carditis plus arthritis. HLA-DR1 antigens were overrepresented in the total group of patients with RF and in all the subgroups studied, excluding the chorea subgroup in which the frequency of HLA-DR1 antigen was not increased. The results reported here indicate that immunogenetic susceptibility to RF may vary according to the major clinical manifestations presented by the patient
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Índice:
LILACS (Américas)
Assunto principal:
Febre Reumática
/
Antígenos HLA
Limite:
Adolescente
/
Adulto
/
Criança
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Medicina (Ribeiräo Preto)
Assunto da revista:
Medicina
Ano de publicação:
2000
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
USP/BR
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