Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis)
Rev. Soc. Bras. Med. Trop
;
35(4): 401-404, jul.-aug. 2002.
Artigo
em Inglês
| LILACS
| ID: lil-331739
ABSTRACT
A dengue fever case is described in a 58-year-old male patient with febrile illness and thrombocytopenia complicated by neurological involvement characterized by transverse myelitis followed by weakness of both legs and flaccid paralysis. Muscle strength was much diminished and bilateral areflexia was observed. Dengue 2 (DEN-2) virus was isolated and the patient sero-converted by hemagglutination-inhibition and IgM-ELISA tests. The RT-PCR test was positive to DEN-2 in acute phase serum and culture supernatant, but negative in the cerebrospinal fluid. After three weeks of hospitalization the patient was discharged. No other infectious agent was detected in the blood and cerebrospinal fluid samples. The patient had full recovery from paralysis six months after the onset of DEN-2 infection.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Dengue
/
Vírus da Dengue
/
Mielite Transversa
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
Medicina Tropical
Ano de publicação:
2002
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Ministério da Saúde/BR
/
Universidade Federal do Pará/BR
/
Universidade do Estado do Pará/BR
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