Human papillomavirus prevalence, viral load and cervical intraepithelial neoplasia in HIV-infected women
Braz. j. infect. dis
;
6(3): 129-135, Jun. 2002.
Artigo
em Inglês
| LILACS, SES-SP
| ID: lil-332322
ABSTRACT
HIV-infected women from S o Paulo city were enrolled in a cross-sectional study on Human Papillomavirus (HPV) and cervical intraepithelial neoplasia (CIN) prevalence and their association with laboratory markers of AIDS, namely HIV viral load and CD(4)(+) cell counts. A cervical specimen was collected and submitted to Hybrid Capture, a test for HPV viral load determination. HPV-DNA was detected in 173 of 265 women (64.5). Twenty (7.5) women were infected by one or more low-risk viruses, 89 (33) by one or more high-risk viruses, and 64 (24) harbored at least one HPV type from each risk group. Abnormal smears were observed in 19 of the patients, though there were no invasive carcinomas. Severely immunosuppressed patients (CD(4)/microL <100) were at the greatest risk of having a cytological abnormality and a high high-risk HPV viral load.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Infecções Tumorais por Vírus
/
Infecções por HIV
/
Neoplasias do Colo do Útero
/
Carga Viral
/
Infecções por Papillomavirus
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo de prevalência
/
Fatores de risco
Limite:
Adolescente
/
Adulto
/
Feminino
/
Humanos
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Braz. j. infect. dis
Ano de publicação:
2002
Tipo de documento:
Artigo
Instituição/País de afiliação:
Casa da AIDS/BR
/
Digene do Brasil/BR
/
Emilio Ribas Institute/BR
/
Institute of Tropical Medicine/BR
/
University of São Paulo/BR
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