Regression of AIDS-related Kaposi's sarcoma following combined antiretroviral treatment
Rev. argent. microbiol
; Rev. argent. microbiol;32(4): 206-208, oct.-dec. 2000.
Article
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| LILACS
| ID: lil-332510
Biblioteca responsável:
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ABSTRACT
The aim of the study was to assess regression of Kaposi's sarcoma (KS) in AIDS patients in Argentina. Eighteen male AIDS patients with human immunodeficiency virus (HIV)-associated Kaposi's sarcoma at different clinical stages received KS specific treatment and/or anti-retroviral therapy. Triple anti-retroviral therapy was given to most of the patients with the exception of four who received zidovudine (ZDV) in combination with another nucleoside analogue but no protease inhibitors. Plasma viral load and CD4+ T lymphocyte number were measured in two blood samples (before and after treatment). Complete remission was found in all patients (five) at KS stage I, three out of eight patients at stage II but in none at stages III and IV. Two out of three patients at KS stage IV did not respond to treatments at all. Three patients at KS stages I and II showed complete remission of sarcoma with only anti-retroviral therapy suggesting that anti-retroviral therapy and non-KS specific chemotherapy can successfully control KS.
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Índice:
LILACS
Assunto principal:
Sarcoma de Kaposi
/
Síndrome da Imunodeficiência Adquirida
/
Fármacos Anti-HIV
Limite:
Adult
/
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Rev. argent. microbiol
Assunto da revista:
MICROBIOLOGIA
Ano de publicação:
2000
Tipo de documento:
Article