Deficiencia de folato y concentraciones elevadas de formato en suero y líquido cefalorraquídeo de pacientes con neuropatía óptica epidémica / Folic acid deficiency and increased concentrations of formate in serum and cerebrospinal fluid of patients with epidemic optical neuropathy
Rev. cuba. med. trop
;
52(1): 21-23, Jan.-Apr. 2000.
Artigo
em Espanhol
| LILACS
| ID: lil-333502
RESUMEN
We studied 62 patients aged 48 years as an average and diagnosed with bilateral optical neuropathy during an epidemics in Pinar del RÝo province. Of these patients, 42 showed the optical form whereas 20 had the mixed form of optical neuropathy. We researched into the levels of formate and folate in serum and cerebrospinal fluid samples and we found a marked deficiency of folates in more than 50 of samples and high formate concentration levels in almost 25 of samples. We concluded that nutritional shortages that lead to a reduction of folates, and the intake of small amounts of methanol in alcoholic drinks could lead to lacking energetic states which would facilitate that the optical nerve be affected and the epidemic optical neuropathy appear.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Doenças do Nervo Óptico
/
Surtos de Doenças
/
Ácido Fólico
/
Deficiência de Ácido Fólico
/
Formiatos
Tipo de estudo:
Estudo de etiologia
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Espanhol
Revista:
Rev. cuba. med. trop
Assunto da revista:
Medicina Tropical
Ano de publicação:
2000
Tipo de documento:
Artigo
País de afiliação:
Cuba
/
Estados Unidos
Instituição/País de afiliação:
Instituto de Neurología y Neurocirugía/CU
/
Medical School of Wisconsin/US
/
University of Southern California/US
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