Predictors of adverse events after percutaneous transluminal coronary angioplasty in a group of Hispanic patients

ABSTRACT

OBJECTIVE: To identify predictors of adverse events after PTCA during hospitalization and after hospital discharge in a private hospital in Puerto Rico. BACKGROUND: A review of the literature shows limited information about predictors of adverse events associated to percutaneous transluminal coronary angioplasty (PTCA) in Hispanic patients. METHODS: This is a non-concurrent prospective study. Baseline variables were analyzed using multivariate logistic regression to identify predictors of adverse events. Data were collected from medical charts and telephone reports from referring physicians. RESULTS: Data from 197 subjects undergoing PTCA were analyzed for this study. Median age of patients was 65 years, and 62.9 of patients were male. Angiographic success rate was 81.6. A total of 8.1 of patients had at least one in-hospital adverse event, and 39.8 had at least one adverse event after hospital discharge. After multivariate analysis, a statistically significant association was found between the presence of at least one lesion with residual stenosis of 50 or greater and the risk of developing adverse events in-hospital (RO 11.75; 95 CI 4.32-31.97). A marginally significant association was found between family history of heart disease (RO 2.75; 95 CI 0.93-8.11) and the risk of adverse events during hospitalization. Family history of heart disease (RO 1.41; 95 CI 0.98-2.04) and the presence of at least one lesion with residual stenosis of 50 or greater (RO 2.87; 95 CI 0.82-10.01) showed marginally significant associations with increased risk for adverse events after discharge. CONCLUSIONS: These findings suggest that the presence of at least one lesion with residual stenosis of 50 or greater and family history of heart disease may be risk factors for adverse events after PTCA during hospitalization and after discharge.