Human red blood cells from prenatal hemopoiesis. Lithium flux (sodium dependent) asymmetry
Biocell
;
24(3): 233-237, Dec. 2000.
Artigo
em Inglês
| LILACS
| ID: lil-335894
ABSTRACT
In red cells from umbilical cord blood it has been referred the existence of lithium fluxes (contralateral sodium dependent) asymmetry. On account of the relevancy of this transport system in some pathologies it is pertinent the study of its kinetics to relate normal with pathological states in which it is affected. Lithium fluxes--contralateral sodium dependent were determined in N-ethylmaleimide treated neonatal red blood cells. Experimental data were fitted by simple Michaelis-Menten kinetics, finding Km and Vmax variables. It was shown the persistency of asymmetry. The independence of sulfhydryl groups (or the occultation of the groups involved to this inhibitor) could explain asymmetry persistence.
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Índice:
LILACS (Américas)
Assunto principal:
Membrana Celular
/
Transporte de Íons
/
ATPase Trocadora de Sódio-Potássio
/
Eritrócitos
/
Lítio
Limite:
Feminino
/
Humanos
/
Gravidez
Idioma:
Inglês
Revista:
Biocell
Assunto da revista:
Clulas
Ano de publicação:
2000
Tipo de documento:
Artigo
País de afiliação:
Argentina
Instituição/País de afiliação:
National University of Rosario/AR
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