Adrenocortical tumors: results of treatment and study of Weiss's score as a prognostic factor
Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo
;
57(6): 251-256, Nov.-Dec. 2002. graf
Artigo
em Inglês
| LILACS
| ID: lil-336457
RESUMO
PURPOSE:
The differential diagnosis between benign and malignant adrenal cortical tumors circumscribed to the gland is controversial. One hundred and seven patients with adrenal cortex tumors (excluding those with primary hyperaldosteronism) were studied to assess the 5-year survival rate of adults, children, patients stratified by pathological stage, and patients stratified according to Weiss's score of <3 or >3.METHODS:
The patients were evaluated both clinically and biochemically. One hundred and five patients underwent surgery and were classified pathologically as stages I, II, III, or IV. The tumors were weighed, measured, and classified according to Weiss's criteria and divided into 2 groups <3 and >3.RESULTS:
After 5 years, the survival rate was 77.5 percent for the whole group, 74.61 percent for the adults, 84.3 percent for the children, 100 percent for stage I, 83.9 percent for stage II, 33 percent for stage III, and 11.7 percent for stage IV groups. Additionally, after 5 years, 100 percent of the patients with tumors with Weiss's score <3 were alive compared to 61.65 percent of those with Weiss's score >3. The average weights of the tumors of score <3 and >3 were 23.38 g ± 41.36 g and 376.3 ± 538.76 g, respectively, which is a statistically significant difference. The average sizes of tumors of Weiss's score <3 and >3 were 3.67 ± 2.2 cm and 9.64 ± 5.8 cm, respectively, which is also a statistically significant difference.CONCLUSIONS:
Weiss's score may be a good prognostic factor for tumors of the adrenal cortex. Additionally, there was a statistically significant difference between the average weight and size of tumors with benign behavior (Weiss's score <3) and those with malignant behavior (Weiss's score >3)
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Neoplasias do Córtex Suprarrenal
/
Carcinoma Adrenocortical
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Adolescente
/
Adulto
/
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
/
Lactente
/
Masculino
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo
Assunto da revista:
Medicina
Ano de publicação:
2002
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
University of Säo Paulo/BR
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