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Lipid and acute-phase protein alterations in HIV-1 infected patients in the early stages of infection: correlation with CD4+ lymphocytes
Treitinger, Arício; Spada, Celso; Silva, Laura Maria D. da; Hermes, Elizabeth Martins; Amaral, Jorge Antônio; Abdalla, Dulcineia Saes Parra.
  • Treitinger, Arício; s.af
  • Spada, Celso; s.af
  • Silva, Laura Maria D. da; s.af
  • Hermes, Elizabeth Martins; s.af
  • Amaral, Jorge Antônio; s.af
  • Abdalla, Dulcineia Saes Parra; s.af
Braz. j. infect. dis ; 5(4): 192-199, Aug. 2001. tab
Artigo em Inglês | LILACS | ID: lil-339409
RESUMO
Lipid and acute-phase protein alterations have been described in various infection diseases, and they have been recorded during the early stages of HIV infection. Lipid and acute-phase protein profiles also have been correlated with cellular immunological abnormalities. To document these correlations during HIV infection, we studied 75 HIV-infected patients and 26 HIV-negative controls. Patients were classified according to the criteria proposed by the Walter Reed army Institute as WR-1 (CD4lymphocytes, 1154+268/mm3), WR-2 (CD4,793+348/mm3) and WR3/4(CD4287+75mm3). Triglycerides, total cholesterol and HDL-cholesterol concentrations were measurede by enzymatic methods. Immunoglobulins (IgA and IgG) and acute-phase proteins (haptoglobin, &,-acid glycoprotein, C-reactive protein and transferrin) were determined by immunonephelometry. Haptoglobin levels were significantly increased in HIV-positive patients and correlated with the progression of HIV-infection (control
Assuntos
Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: Proteínas de Fase Aguda / Infecções por HIV / Soropositividade para HIV / Soronegatividade para HIV / Lipídeos Limite: Humanos Idioma: Inglês Revista: Braz. j. infect. dis Assunto da revista: Doenças Transmissíveis Ano de publicação: 2001 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: Proteínas de Fase Aguda / Infecções por HIV / Soropositividade para HIV / Soronegatividade para HIV / Lipídeos Limite: Humanos Idioma: Inglês Revista: Braz. j. infect. dis Assunto da revista: Doenças Transmissíveis Ano de publicação: 2001 Tipo de documento: Artigo