Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets
Rev. Soc. Bras. Med. Trop
;
35(6): 601-607, nov.-dez. 2002. ilus, tab, graf
Artigo
em Inglês
| LILACS
| ID: lil-340059
ABSTRACT
The effects of high and low-protein diets on the structure of the jejunal mucosa were studied in Schistosoma mansoni infected mice (morphology and histomorphometry). Weaning male albino mice were infected with 80 cercariae, fed with high (20 percent) or low-protein (5 percent) diets and compared to uninfected controls under the same conditions. Mice were sacrificed 12 weeks after infection. Animals submitted to a low-protein diet showed lower weight curves, mainly when infected. In the jejunal mucosa, finger-like villi were the predominant pattern among uninfected high-protein fed animals, while the infected ones showed leaf-shaped and flattened villi in most cases. Undernourished infected mice had 65.7 percent leaf-shaped villi. A significant increase in the number of goblet cells was seen in infected mice. A decrease in the number of absorptive cells was detected in undernourished mice, particularly in infected ones
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Deficiência de Proteína
/
Esquistossomose mansoni
/
Proteínas Alimentares
/
Mucosa Intestinal
/
Jejuno
Limite:
Animais
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
Medicina Tropical
Ano de publicação:
2002
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Escola de Ciências Médicas de Alagoas/BR
/
Fundação Oswaldo Cruz/BR
/
Universidade Federal Fluminense/BR
/
Universidade Federal de Alagoas/BR
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