Species distribution and antifungal susceptibility profile of Candida spp. bloodstream isolates from Latin American hospitals
Mem. Inst. Oswaldo Cruz
;
98(3): 401-405, Apr. 2003. tab
Artigo
em Inglês
| LILACS
| ID: lil-340123
ABSTRACT
From March 1999 to March 2000, we conducted a prospective multicenter study of candidemia involving five tertiary care hospitals from four countries in Latin America. Yeast isolates were identified by classical methods and the antifungal susceptibility profile was determined according to the National Committee for Clinical Laboratory Standards microbroth assay method. During a 12 month-period we were able to collect a total of 103 bloodstream isolates of Candida spp. C. albicans was the most frequently isolated species accounting for 42 percent of all isolates. Non-albicans Candida species strains accounted for 58 percent of all episodes of candidemia and were mostly represented by C. tropicalis (24.2 percent) and C. parapsilosis (21.3 percent). It is noteworthy that we were able to identify two cases of C. lusitaniae from different institutions. In our casuistic, non-albicans Candida species isolates related to candidemic episodes were susceptible to fluconazole. Continuously surveillance programs are needed in order to identify possible changes in the species distribution and antifungal susceptibility patterns of yeasts that may occurs after increasing the use of azoles in Latin American hospitals
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Candida
/
Candidíase
/
Antifúngicos
Tipo de estudo:
Ensaio Clínico Controlado
/
Guia de Prática Clínica
/
Estudo observacional
Limite:
Humanos
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2003
Tipo de documento:
Artigo
País de afiliação:
Argentina
/
Brasil
/
Peru
/
Venezuela
Instituição/País de afiliação:
Hospital Cayetano Heredia/PE
/
Santa Casa de Porto Alegre/BR
/
Universidad de Buenos Aires/AR
/
Universidad del Zulia/VE
/
Universidade Federal de São Paulo/BR
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