Diffusion MRI studies in vascular cognitive impairment and dementia
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
;
25(3): 188-191, set. 2003. ilus
Artigo
em Inglês
| LILACS
| ID: lil-346999
ABSTRACT
Since its introduction more than two decades ago, Magnetic Resonance Imaging (MRI) has not only allowed for visualization of the macrostructure of the CNS, but also has been able to study dynamic processes which constitute the substrate of currently available MRI variants. While conventional Diffusion Weighted Imaging (DWI) permits a robust visualization of lesions just a few minutes after the onset of cerebral ischemia, Diffusion Tensor Imaging (DTI) measures the magnitude and direction of diffusion, leading to the characterization of cerebral white matter (WM) microstructural integrity. In this paper, the potential role of MRI techniques, particularly DTI, for the study of the relationship between changes in the microstructural integrity of WM and cognitive impairment in the context of cerebrovascular disease are discussed. Significant correlations between scores of behavioral measures of cognitive function and regional anisotropy values are an example of the potential efficacy of DTI for in vivo studies of brain connectivity in vascular neurodegenerative conditions
Texto completo:
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Índice:
LILACS (Américas)
Assunto principal:
Imageamento por Ressonância Magnética
/
Demência Vascular
/
Transtornos Cognitivos
Tipo de estudo:
Estudo de etiologia
Limite:
Humanos
Idioma:
Inglês
Revista:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Assunto da revista:
Psiquiatria
Ano de publicação:
2003
Tipo de documento:
Artigo
País de afiliação:
Estados Unidos
Instituição/País de afiliação:
Rush University/US
/
The Chicago Medical School/US
/
University of Illinois at Chicago/US
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