Prevalence of prostate adenocarcinoma according to race in an university hospital

ABSTRACT

OBJECTIVES: To determine the prevalence of prostate cancer and to assess potential associations between race and prostate adenocarcinoma according to age in patients followed in an outpatient service of general urology in an university hospital. MATERIALS AND METHODS: Retrospective study of men aged from 40 to 79 years, followed during the period from 1999 to 2001. Patients were classified according to race in White, Mulatto and Black. Those with abnormal digital rectal examination and/or serum level of prostate specific antigen (PSA) > 4.0 ng/ml, underwent a transrectal prostate biopsy. RESULTS: 580 patients with mean age of 60.7 ± 10.0 years were studied, with 116 Whites (20.0 percent), 276 Mulattos (47.6 percent) and 188 Blacks (32.4 percent). There was no significant difference regarding the mean age (p = 0.62), serum level of PSA (p = 0.65) and prevalence of prostate adenocarcinoma between Whites, Mulattos and Blacks (p = 0.36). While studying the association between race classified in 2 groups (Whites versus Mulattos and Blacks) and prostate adenocarcinoma according to age, no association was found when the total group was assessed, neither among those with age above 60 years old. In the group between 40 and 60 years, even though without statistical significance, the estimate of prevalence ratio was 2.2 (CI 95 percent 0.52 to 9.0; p = 0.38). CONCLUSION: Prostate adenocarcinoma was found in 16.6 percent of the patients aged between 40 and 79 years. We did not find a racial influence in our population.