Anemia aplástica adquirida del adulto. Su tratamiento a propósito de dos casos / Acquired aplastic anemia of the adult: the treatment of two cases
Rev. méd. Chile
;
131(12): 1439-1443, dic. 2003. ilus
Artigo
em Espanhol
| LILACS
| ID: lil-360243
ABSTRACT
Severe aplastic anemia has an elevated mortality if treatment is unsatisfactory. Immunosuppression is the treatment of choice in adults, comparable with allogeneic bone marrow transplant in children. We report two adult patients (both males, aged 59 and 67 years old) who were treated successfully with lymphoglobulin and cyclosporine. The initial response started within 3 months of treatment and was almost complete after 2 years, when cyclosporine was stopped. After three years, both patients have almost normal blood counts, with minor sequels: avascular necrosis of both femoral heads due to the use steroids, that recovered spontaneously in 1 patient and reduced vision due to thrombocytopenic retinal hemorrhages, in the other (Rev Méd Chile 2003; 131: 1439-43).
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Ciclosporinas
/
Imunossupressores
/
Anemia Aplástica
/
Soro Antilinfocitário
Tipo de estudo:
Estudo de etiologia
Limite:
Humanos
/
Masculino
Idioma:
Espanhol
Revista:
Rev. méd. Chile
Assunto da revista:
Medicina
Ano de publicação:
2003
Tipo de documento:
Artigo
País de afiliação:
Chile
Instituição/País de afiliação:
Universidad de Chile/CL
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