Genetic organization and expression of citrate permease in lactic acid bacteria
Genet. mol. res. (Online)
;
3(2): 273-281, jun. 2004.
Artigo
em Inglês
| LILACS
| ID: lil-387948
RESUMO
Citrate is present in many natural substrates, such as milk, vegetables and fruits, and its metabolism by lactic acid bacteria (LAB) plays an important role in food fermentation. The industrial importance of LAB stems mainly from their ability to convert carbohydrates into lactic acid and, in some species, like Lactococcus lactis and Leuconostoc mesenteroides, to produce C4 flavor compounds (diacetyl, acetoin) through citrate metabolism. Three types of genetic organization and gene locations, involving citrate metabolism, have been found in LAB. Citrate uptake is mediated by a citrate permease, which leads to a membrane potential upon electrogenic exchange of divalent citrate and monovalent lactate. The internal citrate is cleaved into acetate and oxaloacetate by a citrate lyase, and oxaloacetate is decarboxylated into pyruvate by an oxaloacetate decarboxylase, yielding a pH gradient through the consumption of scalar protons.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Proteínas de Bactérias
/
Proteínas de Transporte
/
Lactococcus
/
Ácido Láctico
/
Oxo-Ácido-Liases
/
Complexos Multienzimáticos
Idioma:
Inglês
Revista:
Genet. mol. res. (Online)
Assunto da revista:
Biologia Molecular
/
Genética
Ano de publicação:
2004
Tipo de documento:
Artigo
País de afiliação:
França
Instituição/País de afiliação:
Laboratoire de Microbiologie Alimentaire et Industrielle/FR
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