Genetic characterization of the population of São Luís, MA, Brazil

RESUMO

Five loci (vWA1, F13A1, D12S67, Apo-B and D1S80) were investigated by polyacrylamide gel electrophoresis followed by silver staining in a sample of 177 individuals from the population of São Luís, State of Maranhão, Brazil. A total of 70 different alleles were identified. A statistically significant deviation from the Hardy-Weinberg equilibrium was observed in a single locus (F13A1, p = 0.0075). The average heterozygosity (H) was estimated at 77.7 percent, the mean number of alleles per locus as 14. The PD (capacity of genotype differentiation at each locus) ranged from 88.9 percent (vWA1) to 96.7 percent (F13A1). The combined PE (power of exclusion) of these five loci was 99.8 percent. In terms of racial admixture (42 percent European, 39 percent Indian, and 19 percent African Black ancestry), São Luís presented an estimate similar to Belém, another trihybrid Amazonian population.