Mast cell changes in experimental diabetes: focus on attenuation of allergic events
Mem. Inst. Oswaldo Cruz
;
100(supl.1): 121-125, Mar. 2005.
Artigo
em Inglês
| LILACS
| ID: lil-402187
ABSTRACT
The prevalence of atopic diseases and diabetes is increasing worldwide though the concurrence of these pathologies in individual patients is found less frequent than it would be predicted. Moreover, co-existence of diabetes and allergy is generally marked by attenuation of their respective symptoms, and effective treatment of one disease exacerbates the other. This review gives an update of the state-of-the-art concerning the intercurrence of allergy and diabetes, particularly focusing on the consequences to the allergen-evoked vascular and cellular changes. It is proposed that the reduction in mast cell numbers and reactivity may be a pivotal mechanism behind the mutual exclusion phenomenon.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Diabetes Mellitus Experimental
/
Hipersensibilidade
/
Mastócitos
Tipo de estudo:
Estudo de etiologia
/
Fatores de risco
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2005
Tipo de documento:
Artigo
País de afiliação:
Brasil
/
França
Instituição/País de afiliação:
Instituto Oswaldo Cruz/BR
/
Université de Rennes/FR
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