Probiotics enhance the recovery of gut atrophy in experimental malnutrition
Biocell
;
28(2): 143-150, ago. 2004. tab
Artigo
em Inglês
| LILACS
| ID: lil-403131
RESUMO
AIM:
The aim of this study was to evaluate the effect of probiotics on the recovery of the bowel atrophy induced by malnutrition in rats.METHODS:
Twenty-and-six Wistar rats (200-250 g) were fed with either a normoproteic (sham group, n=6) or a free-protein diet (n=20)during 12 days. Twelve malnourished rats were randomized to recover during 15 days with either a hydrolyzed diet (control group, n=6) or the same diet enriched with probiotics (Streptococcus thermophilus and Lactobacilus helveticus; probiotic group, n=6).RESULTS:
probiotic group showed similar gain of body, liver and bowel weight than controls. At the jejunum, both thevillus height (383±49 vs. 321±46mm; p=0,04) and crypt depth (157±31 vs. 125±10mm; p=0,04) were greater in probiotic group than in controls. The crypt depth at the cecum (214±22 vs. 169±43mm; p=0,05) and the wall width at both the cecum (410±18 vs. 340±61mm; p=0,02) and sigmoid (479±130 vs. 330±62mm; p=0,03) were higher in probiotic than in control group.CONCLUSION:
Streptococcus thermophillus and Lactobacillus helveticus enhance the recovery of gut atrophy induced by malnutrition. Probiotics can be useful as oral adjuvants during the recovery of malnutrition.
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Índice:
LILACS (Américas)
Assunto principal:
Proteínas Alimentares
/
Probióticos
/
Desnutrição
/
Mucosa Intestinal
/
Intestinos
Limite:
Animais
Idioma:
Inglês
Revista:
Biocell
Assunto da revista:
Clulas
Ano de publicação:
2004
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
The Federal University of Mato Grosso/BR
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