Síndrome miasteniforme de Lambert-Eaton idiopático: Report of one case / Idiopathic Lambert-Eaton myasthenic syndrome
Rev. méd. Chile
;
134(2): 217-223, feb. 2006. tab, graf
Artigo
em Espanhol
| LILACS
| ID: lil-425972
ABSTRACT
Lambert-Eaton myasthenic syndrome (LEMS) is an autoinmune idiopathic or paraneoplastic syndrome producing antibodies agaisnt presynaptic voltage calcium channels. The clinical features of patients with LEMS are muscle weakness and autonomic dysfunction. We report a 40 years old man with a four years history of proximal weakness, absent tendon reflexes and dry mouth. The diagnosis was confirmed by characteristic electromyographic findings, showing a low-amplitude muscle response that increased dramatically after activation. Circulating antibodies to voltage-gated calcium channel were present. The search for malignant tumors was negative. The patient was treated with prednisone and azathioprine and after four months, he was able to walk and signs of autonomic dysfunction started to subside.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Síndrome Miastênica de Lambert-Eaton
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Espanhol
Revista:
Rev. méd. Chile
Assunto da revista:
Medicina
Ano de publicação:
2006
Tipo de documento:
Artigo
País de afiliação:
Chile
Instituição/País de afiliação:
Centro de Referencia de Salud Dr/CL
/
Centro de Referencia de Salud Dr. Salvador Allende Gossens/CL
/
Universidad Católica de Chile/CL
/
Universidad de Chile/CL
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