Función de los músculos inspiratorios, parámetros hemodinámicos y disnea en pacientes con estenosis mitral / Inspiratory muscle function, hemodynamic parameters and dyspnea in patients with mitral valve stenosis
Rev. méd. Chile
;
134(5): 556-564, mayo 2006. ilus, tab
Artigo
em Espanhol
| LILACS
| ID: lil-429861
ABSTRACT
Background:
The mechanism involved in dyspnea in patients with mitral valve stenosis (MS) is not completely understood.Aim:
To evaluate in patients with MS, changes in hemodynamic parameters during the assessment of inspiratory muscle endurance (IME) and the relationship between IME, hemodynamics and dyspnea. Subjects andmethods:
We studied 13 patients (9 in NYHA class II and 4 in class III). Endurance was evaluated using a two minute incremental threshold loading test, to obtain the maximal sustainable inspiratory pressure (SIP), and maximal inspiratory load (MIL). During the test, cardiac output (CO), mean pulmonary and capillary pressures (PAP and PCP, respectively), were evaluated.Results:
Compared to six normal subjects, MS patients had reduced SIP and MIL (p <0.01), which correlated with baseline index of dyspnea (r= 0.57 and r=0.52, respectively, p <0.05). At the end of the test period, basal CO, cardiac index (CI), PAP and PCP increased from 3.4 to 4.0 l/min-1; 2.1 to 2.5 l/min-1/m-2; 15 to 25 and 11 to 18 mmHg, respectively (p <0.01). No relationship between IME and hemodynamic parameters was found.Conclusions:
IME is reduced and is closely related to dyspnea in these patients with MS. The observed low CI, suggests that muscle underperfusion could contribute to this dysfunction during the inspiratory effort.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Pressão Sanguínea
/
Músculos Respiratórios
/
Capacidade Inspiratória
/
Dispneia
/
Estenose da Valva Mitral
Tipo de estudo:
Estudos de avaliação
/
Estudo observacional
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Espanhol
Revista:
Rev. méd. Chile
Assunto da revista:
Medicina
Ano de publicação:
2006
Tipo de documento:
Artigo
/
Documento de projeto
País de afiliação:
Chile
Instituição/País de afiliação:
Hospital Regional de Concepción/CL
/
Universidad de Concepción/CL
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