Respiratory syncytial virus (RSV) in infants hospitalized for acute lower respiratory tract disease: incidence and associated risks
Braz. j. infect. dis
;
10(5): 357-361, Oct. 2006. graf, tab
Artigo
em Inglês
| LILACS
| ID: lil-440697
ABSTRACT
Respiratory syncytial virus (RSV) is one of the main causes of acute lower respiratory tract infections worldwide. We examined the incidence and associated risks for RSV infection in infants hospitalized in two university hospitals in the state of São Paulo. We made a prospective cohort study involving 152 infants hospitalized for acute lower respiratory tract infections (ALRTI) in two university hospitals in Campinas, São Paulo, Brazil, between April and September 2004. Clinical and epidemiological data were obtained at admission. RSV was detected by direct immunofluorescence of nasopharyngeal secretions. Factors associated with RSV infection were assessed by calculating the relative risk (RR). The incidence of RSV infection was 17.5 percent. Risk factors associated with infection were gestational age less than 35 weeks (RR 4.17; 95 percent confidence interval (CI) 2.21-7.87); birth weight less than or equal to 2,500 grams (RR 2.69; 95 percent CI 1.34-5.37); mother's educational level less than five years of schooling (RR 2.28; 95 percent CI 1.13-4.59) and pulse oximetry at admission to hospital lower than 90 percent (RR 2.19; 95 percent CI 1.10-4.37). Low birth weight and prematurity are factors associated with respiratory disease due to RSV in infants. Low educational level of the mother and poor socioeconomic conditions also constitute risk factors. Hypoxemia in RSV infections at admission indicates potential severity and a need for early oxygen therapy.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Infecções Respiratórias
/
Infecções por Vírus Respiratório Sincicial
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Estudo observacional
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Lactente
/
Masculino
/
Recém-Nascido
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Braz. j. infect. dis
Assunto da revista:
Doenças Transmissíveis
Ano de publicação:
2006
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
State University of Campinas/BR
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