Looking Beyond Tobacco and Alcohol: The Role of Lifestyle and Other Environmental Risk Factors for Laryngeal Cancer
Appl. cancer res
;
25(1): 10-19, Jan.-Mar. 2005.
Artigo
em Inglês
| LILACS, Inca
| ID: lil-442296
ABSTRACT
Laryngeal cancer incidence in São Paulo, Brazil, is one of the highest in the world. OBJECTIVE:
This hospitalbasedcase-control study was designed to investigate exposure-disease relationship between larynx cancer andsmoking and drinking history, diet, occupational exposures and other characteristics. MATERIAL ANDMETHODS:
The study was conducted in 3 metropolitan areas in Brazil São Paulo (South-east), Curitiba (South)and Goiânia (Central-west). We have analyzed information on demographics, occupational history, environmental exposures, tobacco smoking and alcoholdrinking habits obtained from interviews with 194 cases and 804 controls (non-cancer inpatients) matched on 5-year age group, gender, hospital catchments area, and trimester of admission.RESULTS:
Tobacco and alcohol consumption were the most important factors for prediction of laryngeal cancer. Other important riskfactors were indoor exposure to wood stove fumes (RR=2.6), woodworking (RR=1.9), family history of cancer(RR=2.1), and high consumption of coffee and chimarrão(a kind of maté tea ). There was a protective effect for the consumption of citric fruits and forcarotene-rich vegetables.CONCLUSION:
regionally specific lifestyle (chimarrão, high consumption of woodworking, and family history of cancer may be responsible for a substantial proportion of incidentlaryngeal cancer cases.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Nicotiana
/
Neoplasias Laríngeas
/
Fatores de Risco
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Appl. cancer res
Assunto da revista:
Neoplasias
Ano de publicação:
2005
Tipo de documento:
Artigo
País de afiliação:
Brasil
/
Canadá
Instituição/País de afiliação:
Hospital Araújo jorge/BR
/
Hospital Erasto Gaertner/BR
/
Hospital Heliópolis/BR
/
Hospital do Câncer A. C. Camargo/BR
/
McGill University/CA
Similares
MEDLINE
...
LILACS
LIS