Cytoreductive Surgery and Intraperitoneal Hyperthermic Chemotherapy in the Treatment of Peritoneal Dissemination of Neoplasias: Preliminary Results with Closed Perfusion Technique
Appl. cancer res
;
25(2): 82-89, Apr.-June 2005.
Artigo
em Inglês
| LILACS, Inca
| ID: lil-442300
ABSTRACT
OBJECTIVE:
to describe preliminary results ofcytoreductive surgery and intraperitoneal hyperthermicchemotherapy in the treatment of peritonealcarcinomatosis from a brazilian single institution.MATERIALS ANDMETHODS:
a short cohort study wascarried out. 26 patients and 28 procedures wereperformed consecutively between March 2001 and June2005. 17 patients (65.4%) were treated for pseudomyxomaperitonei, 4 patients had mesothelioma, 2 carcinomatosisfrom colorectal cancer origin, 2 from ovary cancer and 1had peritoneal sarcomatosis. All cases were treated withclosed perfusion technique. The Completeness ofCytoreduction Score was used to classify the radicalityof the procedure and the NIH Commom Toxicity Criteriawas used to classify the complications.RESULTS:
CC0and CC1 resections were achieved in 24 cases (85.7%).Grade 3 or 4 toxicity were observed in 5 cases (17.8%)and two patients died (7.1%). Severe complications weresignificant associated with the duration of surgery (morethan 10 hours).CONCLUSION:
this radical treatment ofperitoneal carcinomatosis envolves high morbidity andmortality rates and must be conducted in referral centerswith multiprofessional teams and carefully selection ofpatients.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Neoplasias Peritoneais
/
Tratamento Farmacológico
Tipo de estudo:
Estudo observacional
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Appl. cancer res
Assunto da revista:
Neoplasias
Ano de publicação:
2005
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Hospital do Câncer A. C. Camargo/BR
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