Detección de la heterogeneidad molecular de Trypanosoma cruzi / Detection of molecular heterogeneity of Trypanosoma cruzi
Rev. Soc. Bras. Med. Trop
;
38(supl.2): 77-83, 2005. tab
Artigo
em Espanhol
| LILACS
| ID: lil-444170
ABSTRACT
Congenital transmission of T. cruzi in Cochabamba affects 6% of newborns from infected mothers. Only limited information is available on the type of transmitted parasites. However, it is well established that T. cruzi isolated from various vectors as well from host animals are highly heterogeneous. In our presentation we analyse aspects of molecular heterogeneity of T. cruzi and we review methods used for the molecular typing of T. cruzi lineages. Experimentally, we performed the PCR amplification of [quot ]Sequence-characterised region Markers[quot ] for typing T. cruzi isolated from umbilical blood of newborns in Cochabamba. We compared these results with those we obtained from general infected population. All 16 analysed, congenitally infected samples were of lineage IId. Our data also indicated that this lineage was found in about 80% of samples originated from general infected population in Cochabamba.
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Índice:
LILACS (Américas)
Assunto principal:
Trypanosoma cruzi
/
Doença de Chagas
/
Heterogeneidade Genética
Tipo de estudo:
Estudo diagnóstico
Limite:
Animais
/
Humanos
Idioma:
Espanhol
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
Medicina Tropical
Ano de publicação:
2005
Tipo de documento:
Artigo
/
Congresso e conferência
País de afiliação:
Bélgica
/
Bolívia
Instituição/País de afiliação:
Universidad Mayor de San Simón (UMSS)/BO
/
Université Libre de Bruxelles/BE
/
Université Livre de Bruxelles/BE
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