Community-acquired pneumonia by Chlamydophila pneumoniae: a clinical and incidence study in Brazil
Braz. j. infect. dis
;
11(1): 75-82, Feb. 2007. tab, ilus
Artigo
em Inglês
| LILACS
| ID: lil-454709
ABSTRACT
As there was not any data on Chlamydia pneumoniae (TWAR) infections in Brazil so far, a prospective cohort study of adult patients hospitalized due to CAP was carried out for one year in a Brazilian university general hospital to detect the incidence of CAP by Chlamydophila pneumoniae (TWAR) for one year. During a whole year 645 consecutive patients hospitalized due to an initial presumptive diagnosis of respiratory diseases by ICD-10 (J00-J99), excluding upper respiratory diseases, were screened; 59 consecutive patients with CAP were diagnosed. They had determinations of serum antibodies to C. pneumoniae by microimmunofluorescence at the Infectious Diseases Laboratory of University of Louisville (KY, USA); 37 patients (63.8 percent) had seroreactivity to TWAR antigens, from which 23 (39.6 percent) had previous infection; 3 patients (5.2 percent) were diagnosed with CAP by TWAR and got cured. The incidence of TWAR CAP in our hospital by seroconversion was 5.2 percent. Our incidence of 5.2 percent is probably underestimated since TWAR culture was not available; we suggest that Real-Time PCR be used along with other diagnostic methods in future studies to detect the actual incidence of TWAR CAP. We propose that the serological criterion of IgM >1:16 alone to the diagnosis of acute infection by TWAR are discontinued due a lack of specificity.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Imunoglobulina G
/
Imunoglobulina M
/
Infecções por Chlamydia
/
Chlamydophila pneumoniae
/
Pneumonia Bacteriana
Tipo de estudo:
Estudo diagnóstico
/
Estudo de incidência
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Braz. j. infect. dis
Assunto da revista:
Doenças Transmissíveis
Ano de publicação:
2007
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Federal University of RS/BR
/
Federal University of Rio Grande do Sul/BR
/
Santa Casa de Misericórdia de Porto Alegre/BR
Similares
MEDLINE
...
LILACS
LIS