The impact of dengue on liver function as evaluated by aminotransferase levels
Braz. j. infect. dis
;
11(4): 407-410, Aug. 2007. graf, tab
Artigo
em Inglês
| LILACS
| ID: lil-460701
ABSTRACT
The objective of this study was to evaluate the impact of dengue virus infection on liver function by measuring aminotransferase in blood samples from patients serologically diagnosed by according to two MAC-ELISA protocols. Degrees of liver damage were classified according to aminotransferase levels: grade A - normal enzyme levels; grade B - increased levels of at least one of the enzymes; grade C - increased, with at least one of the enzymes being at levels higher than three times the upper reference values; grade D - acute hepatitis, with aminotransferase levels at least ten times their normal values. Of the 169 serologically confirmed cases of dengue at the dengue referral center in Campos dos Goytacazes in the state of Rio de Janeiro, Brazil, 65.1 percent had abnormal aminotransferase levels: 81 cases being classified as grade B, 25 as grade C and 3 as grade D. A further 34.9 percent of cases had normal enzyme levels and were classified as grade A. Liver damage is a common complication of dengue infection and aminotransferase levels are a valuable marker for monitoring these cases.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Aspartato Aminotransferases
/
Dengue
/
Alanina Transaminase
/
Fígado
Tipo de estudo:
Guia de Prática Clínica
Limite:
Adolescente
/
Adulto
/
Idoso
/
Criança
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Braz. j. infect. dis
Assunto da revista:
Doenças Transmissíveis
Ano de publicação:
2007
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Dengue Reference Center/BR
/
FIOCRUZ/BR
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