Estrôncio e osteodistrofia de origem renal: breve revisão da literatura / Strontium and renal osteodystrophy: brief review of literature

ABSTRACT

Strontium is the more abundant element in the earth representing almost 0.34 per cent of the whole earth eruptive igneous rocks. Is is naturally presnt in food, water, air and soil and also used in many industrial activities. It is absorbed in the intestinal mucosa, stored in bone tisue and excreted by the kidney. Some metals such as aluminium and strontium are found in dialysis solutions and medications used as a phosphate binder. Several studies have shown the multifactorial etiology of renal osteodystrophy associated with dialysis as well as the important role of metals, such as aluminium and strontium, on the disease development. This study is a brief review of the literature focusing on the toxic action of strontium in bone and its role in the renal osteodystrophy development...