Immunoelectronic localization of myosin-Va in rat cerebellum
Braz. j. morphol. sci
;
22(4): 211--214, Oct.-Dec. 2005. ilus
Artigo
em Inglês
| LILACS
| ID: lil-468028
ABSTRACT
Myosin V is an unconventional type of actin-binding myosin that participates in cytoplasmic organelle transport. Although this unconventional myosin has been extensively studied, its subcellular localization in the mammalian cerebellum has not been determined. In this work, we used an antibody against the tail domain of the myosin-Va heavy chain and a secondary antibody labeled with protein A-gold (15 nm) to study the subcellular distribution of this protein. Myosin-Va was found in the cytoplasm, where it was associated with a filament (probably actin). This protein was also detected in the plasma membrane of axons and dendrites in the molecular layer in rat cerebellum.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Células de Purkinje
/
Proteína Estafilocócica A
/
Telencéfalo
/
Miosina Tipo V
/
Fenômenos Fisiológicos do Sistema Nervoso
Limite:
Animais
Idioma:
Inglês
Revista:
Braz. j. morphol. sci
Assunto da revista:
Anatomia
Ano de publicação:
2005
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Federal University of Goiás/BR
/
Federal University of Uberlândia/BR
/
University of Patos de Minas/BR
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