Biocompatibility of the Prime & Bond 2.1, Prime & Bond NT and Scothbond MP Primer adhesive systems

ABSTRACT

The objective of this study was to verify the biocompatibility of dental adhesives (Prime & Bond 2.1; Prime & Bond NT and Scotchbond MP). Thirty-six male rats (Rattus norvegicus) received artificial sponges containing the adhesive materials in their back, and they were polymerized before suture. As a control, one group had sponges containing water. Each group consisted of 9 rats with two implants, resulting in 18 samples per group. Three animals of each group were killed after 7, 15 and 30 days and the tissue was analyzed. At sevenday period, inflammation was acute and severe in all other groups, except water. After 15 days, Prime & Bond 2.1 and Prime & Bond NT groups showed a more severe inflammatory infiltrate with foci of neutrophils inside the cavity border when compared with the Scotchbond Primer. After 30 days, in the control group the cavity was shown to be filled by well organized granulomas next to the sponge samples. Prime & Bond 2.1 and Prime & Bond NT groups maintained intense inflammatory process when compared with the Scotchbond Primer MP group. The present results showed that Scotchbond MP Primer Group demonstrated better biocompatibility than the other two groups.