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Response of the periapical tissue of dogs' teeth to the action of citric acid and EDTA
Sperandio, Cristina Berthold; Silveira, Luiz Fernando Machado; Araújo, Lenita Aver de; Martos, Josué; Malshe, Ashwin.
  • Sperandio, Cristina Berthold; Federal University of Pelotas. Dental School. Department of Clinics. Pelotas. BR
  • Silveira, Luiz Fernando Machado; Federal University of Pelotas. Dental School. Department of Clinics. Pelotas. BR
  • Araújo, Lenita Aver de; Federal University of Pelotas. Dental School. Department of Clinics. Pelotas. BR
  • Martos, Josué; Federal University of Pelotas. Dental School. Department of Clinics. Pelotas. BR
  • Malshe, Ashwin; State University of New York. New York. US
J. appl. oral sci ; 16(1): 59-63, Jan.-Feb. 2008. ilus, tab
Artigo em Inglês | LILACS | ID: lil-472691
ABSTRACT
The purpose of this study was to analyze the inflammatory response of dog's periapical tissues to 17 percent trisodium EDTA salt (pH 8.0) and 1 percent citric acid (pH 2.0). Saline was used as a control. Six adult dogs were used as the biological model of the study. The experimental units comprised 56 roots of mandibular molars (first and second) and premolars (first, second and third). After coronal opening, pulpectomy and root canal instrumentation were performed using the above-mentioned irrigating solutions. After 24 and 48 hours, the animals were euthanized and the teeth and their supporting tissues were removed and histologically processed. The sections were stained with hematoxylin and eosin and analyzed histopathologically with a light microscope at x100 magnification. The histological analysis focused on the occurrence of acute inflammatory response. The presence of swelling, vasodilatation and inflammatory cells were evaluated and the degree of inflammation was determined for each case. Data were analyzed by Fisher's exact test using the SPSS software with a confidence interval of 95 percent (p<0.05). 17 percent EDTA and 1 percent citric acid caused inflammatory responses in dog's periapical tissues with no significant differences to each other or to saline (control) at either the 24-hour (p=0.482) or 48-hour (p=0.377) periods. It may be concluded that the inflammatory response was of mild intensity for the tested substances.
Assuntos

Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: Tecido Periapical / Irrigantes do Canal Radicular / Materiais Biocompatíveis / Ácido Edético / Ácido Cítrico Tipo de estudo: Estudo prognóstico Limite: Animais Idioma: Inglês Revista: J. appl. oral sci Assunto da revista: Odontologia Ano de publicação: 2008 Tipo de documento: Artigo País de afiliação: Brasil / Estados Unidos Instituição/País de afiliação: Federal University of Pelotas/BR / State University of New York/US

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Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: Tecido Periapical / Irrigantes do Canal Radicular / Materiais Biocompatíveis / Ácido Edético / Ácido Cítrico Tipo de estudo: Estudo prognóstico Limite: Animais Idioma: Inglês Revista: J. appl. oral sci Assunto da revista: Odontologia Ano de publicação: 2008 Tipo de documento: Artigo País de afiliação: Brasil / Estados Unidos Instituição/País de afiliação: Federal University of Pelotas/BR / State University of New York/US