El tamaño de los tumores suprarrenales ¿está en relación al tiempo de evolución o expresa una diferencia biológica? / Is adrenal tumor size related to evolution time or does it represent a biological difference?
Rev. méd. Chile
; 135(12): 1526-1529, dic. 2007. tab
Article
em Es
| LILACS
| ID: lil-477982
Biblioteca responsável:
BR1.1
ABSTRACT
Background:
Adrenal tumor (AT) malignancy has been related to tumor size. Since laparoscopic surgery is being used, smaller adrenal tumors are being excised.Aim:
To evaluate eventual clinical and histológica! differences between adrenal tumors smaller than 4 cm. and those larger than 6 cm. Patients andMethods:
Retrospective review of pathological reports and clinical records of patients operated for adrenal tumors, dividing them in two groups. Group 1 had 29patients aged 52 ± 13 years with AT < 4 cm operated during the period 2000-2005, and Group 2 was formed by 52 patients aged 46 ±18 years with AT >6 cm operated between 1984-2005- Tumors between 4 and 6 cm were not included in the study to establish clear cut differences between groups.Results:
Tumors were functional in 40 and 41 percent of cases in groups 1 and 2 respectively. Fifty percent of functional tumors of group 1 were pheochromocytomas and the rest secreted aldosterone. In group 2, 66 percent of tumors were phechromocytomas and no aldosterone secreting tumors were found. Fifty two and eight percent of tumors in Groups 1 and 2 were adenomas, respectively (p <0.001). Nineteen tumors of group 2 were malignant, compared with one of group 1 (p <0.001).Conclusions:
The tumor size of adrenal cortical tumors may represent biological differences, suggesting two different tumor populations. At time of diagnosis adrenal carcinomas are almost always larger than 6 cm.Palavras-chave
Texto completo:
1
Índice:
LILACS
Assunto principal:
Carcinoma
/
Neoplasias das Glândulas Suprarrenais
/
Glândulas Suprarrenais
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
Limite:
Female
/
Humans
/
Male
Idioma:
Es
Revista:
Rev. méd. Chile
Assunto da revista:
MEDICINA
Ano de publicação:
2007
Tipo de documento:
Article