Adenoviruses C in non-hospitalized Mexican children older than five years of age with acute respiratory infection
Mem. Inst. Oswaldo Cruz
;
103(2): 195-200, Mar. 2008. graf, tab
Artigo
em Inglês
| LILACS
| ID: lil-480634
ABSTRACT
Adenoviruses (AdV) are commonly involved in acute respiratory infections (ARI), which cause high morbidity and mortality in children. AdV are grouped in six species (A-F), which are associated with a wide range of diseases. The aim of this study was to identify the AdV species infecting non-hospitalized Mexican children with ARI symptoms, attending to the same school. For that, a PCR/RFLP assay was designed for a region of the hexon gene, which was chosen, based on the bioinformatical analysis of AdV genomes obtained from GenBank. A total of 100 children's nasopharyngeal samples were collected from January to June, 2005, and used for viral isolation in A549 cells and PCR/RFLP analysis. Only 15 samples produced cytopathic effect, and in all of them AdV C was identified. AdV C was also identified in eight additional nasopharyngeal samples which were negative for viral isolation. In summary, this outpatient population showed a rate of AdV infection of 23 percent, and only AdV C was detected.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Infecções Respiratórias
/
Infecções por Adenovirus Humanos
/
Adenovírus Humanos
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Limite:
Criança
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
México
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2008
Tipo de documento:
Artigo
/
Documento de projeto
País de afiliação:
México
Instituição/País de afiliação:
Instituto Nacional de Enfermedades Respiratorias/MX
/
Instituto Politécnico Naciona/MX
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