Protein thermostability in Archaea and Eubacteria
Genet. mol. res. (Online)
;
5(4): 816-827, 2006.
Artigo
em Inglês
| LILACS
| ID: lil-482077
ABSTRACT
In order to survive at high temperatures, thermophilic prokaryotes (Archaea and Eubacteria) adopt different strategies. Among several important contributing factors for stability of proteins are CG-rich codons, the ratio of charged amino acids compared to uncharged amino acids, ionic interactions, amino acid preferences and their distribution, post-translational modifications, and solute accumulation. However, these factors may differ from taxon to taxon, both within and between species depending upon the composition of proteins found in these organisms. This is exemplified in the case of differences in strategies adopted by soluble proteins and membrane proteins. Therefore, it appears that no single factor or combination of factors together can be universally attributed to the provision of thermal stability in proteins.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Termodinâmica
/
Bactérias
/
Proteínas de Bactérias
/
Archaea
/
Proteínas Arqueais
/
Temperatura Alta
Idioma:
Inglês
Revista:
Genet. mol. res. (Online)
Assunto da revista:
Biologia Molecular
/
Genética
Ano de publicação:
2006
Tipo de documento:
Artigo
País de afiliação:
Índia
Instituição/País de afiliação:
JN Vyas University/IN
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