Cytogenetics of genetic counseling patients in Pelotas, Rio Grande do Sul, Brazil
Genet. mol. res. (Online)
;
3(3): 303-308, 2004. tab
Artigo
em Inglês
| LILACS
| ID: lil-482176
ABSTRACT
From 1986 to 2002, we examined the chromosomal composition of 916 patients attended by two genetic counseling services in the city of Pelotas, in the Brazilian State of Rio Grande do Sul, to determine the genetic causes of their disturbances. Patterns of G-banding using trypsin and Giemsa (GTG) and C-banding using barium and Giemsa (CBG) were studied using phytohemagglutinin M-stimulated lymphocytes cultured from peripheral blood. Among the patients, 110 had Down's syndrome, 7 had Edward's syndrome, 4 had Patau's syndrome, 29 had Turner's syndrome, 5 had Klinefelter's syndrome, and 3 had [quot ]cri-du-chat[quot ] syndrome. Abnormal chromosomes were observed in 29.3% of the patients. Most of these (56.3%) were numerical abnormalities, with the remaining being structural variants.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Aberrações Cromossômicas
/
Bandeamento Cromossômico
/
Transtornos Cromossômicos
/
Aconselhamento Genético
Limite:
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Genet. mol. res. (Online)
Assunto da revista:
Biologia Molecular
/
Genética
Ano de publicação:
2004
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade Católica de Pelotas/BR
/
Universidade Federal de Pelotas/BR
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