In vivo effects of Buthus occitanus tunetanus and Androctonus australis garzoni scorpion venoms on pregnant and non-pregnant rats
J. venom. anim. toxins incl. trop. dis
;
14(2): 366-371, 2008. tab
Artigo
em Inglês
| LILACS, VETINDEX
| ID: lil-484571
ABSTRACT
Scorpion envenomation in pregnant victims has been scarcely studied. Accidents with venomous animals can induce serious injuries for both mothers and embryos. In the current work, the lethality of Buthus occitanus tunetanus (Bot) and Androctonus australis garzoni (Aag) venoms was assessed in pregnant and non-pregnant murine rat models. The median lethal dose (LD50) was determined following the Spearman-Karber method. Our results showed great similarities of envenomation symptoms between term-pregnant and nonmated rats. An unusual vaginal bleeding was also seen in pregnant rats envenomed with Bot and Aag venoms. Our findings suggest that gestation may increase the venoms toxicity in rats.(AU)
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Venenos de Escorpião
/
Picadas de Escorpião
/
Dose Letal Mediana
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
/
Gravidez
Idioma:
Inglês
Revista:
J. venom. anim. toxins incl. trop. dis
Ano de publicação:
2008
Tipo de documento:
Artigo
Instituição/País de afiliação:
Pasteur Institute of Tunis/TN
/
Service of Communitarian Medicine and Epidemiology/TN
/
University of Sfax/TN
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