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Prostatic cryptococcosis: a case report
Chang, M. R; Paniago, A. M. M; Silva, M. M; Lazéra, M. S; Wanke, B.
  • Chang, M. R; Federal University of Mato Grosso do Sul. Department of Pharmacy-Biochemistry. Campo Grande. BR
  • Paniago, A. M. M; Federal University of Mato Grosso do Sul. Department of Internal Medicine. Campo Grande. BR
  • Silva, M. M; University for Development of the State and the Pantanal Region. Medicine Program. Campo Grande. BR
  • Lazéra, M. S; Oswaldo Cruz Foundation. Evandro Chagas Institute of Clinical Research. Mycology Service. Rio de Janeiro. BR
  • Wanke, B; Oswaldo Cruz Foundation. Evandro Chagas Institute of Clinical Research. Mycology Service. Rio de Janeiro. BR
J. venom. anim. toxins incl. trop. dis ; 14(2): 378-385, 2008. ilus, tab
Artigo em Inglês | LILACS | ID: lil-484573
ABSTRACT
Cryptococcosis is a systemic mycosis usually affecting immunodeficient individuals. In contrast, immunologically competent patients are rarely affected. Dissemination of cryptococcosis usually involves the central nervous system, manifesting as meningitis or meningoencephalitis. Prostatic lesions are not commonly found. A case of prostate cryptococcal infection is presented and cases of prostatic cryptococcosis in normal and immunocompromised hosts are reviewed. A fifty-year-old HIV-negative man with urinary retention and renal insufficiency underwent prostatectomy due to massive enlargement of the organ. Prostate histopathologic examination revealed encapsulated yeast-like structures. After 30 days, the patient's clinical manifestations worsened, with headache, neck stiffness, bradypsychia, vomiting and fever. Direct microscopy of the patient's urine with China ink preparations showed capsulated yeasts, and positive culture yielded Cryptococcus neoformans. This fungus was later isolated from cerebrospinal fluid and blood cultures, demonstrating thus its dissemination. The patient was discharged after 27 days in hospital and, despite a regimen of amphotericin B, he died four months later. This case points to cryptococcosis as a possible cause of prostatic disease and reinforces the importance of communication between the medical team and pathology and microbiology laboratories aiming at a more accurate diagnosis and successful treatment.
Assuntos

Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: Próstata / Doenças Prostáticas / Criptococose Limite: Humanos / Masculino Idioma: Inglês Revista: J. venom. anim. toxins incl. trop. dis Assunto da revista: Toxicologia Ano de publicação: 2008 Tipo de documento: Artigo País de afiliação: Brasil Instituição/País de afiliação: Federal University of Mato Grosso do Sul/BR / Oswaldo Cruz Foundation/BR / University for Development of the State and the Pantanal Region/BR

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Texto completo: DisponíveL Índice: LILACS (Américas) Assunto principal: Próstata / Doenças Prostáticas / Criptococose Limite: Humanos / Masculino Idioma: Inglês Revista: J. venom. anim. toxins incl. trop. dis Assunto da revista: Toxicologia Ano de publicação: 2008 Tipo de documento: Artigo País de afiliação: Brasil Instituição/País de afiliação: Federal University of Mato Grosso do Sul/BR / Oswaldo Cruz Foundation/BR / University for Development of the State and the Pantanal Region/BR