Antimicrobial activity of Brazilian copaiba oils obtained from different species of the Copaifera genus
Mem. Inst. Oswaldo Cruz
;
103(3): 277-281, May 2008. ilus, graf, tab
Artigo
em Inglês
| LILACS
| ID: lil-485220
ABSTRACT
The antimicrobial activity of copaiba oils was tested against Gram-positive and Gram-negative bacteria, yeast, and dermatophytes. Oils obtained from Copaifera martii, Copaifera officinalis, and Copaifera reticulata (collected in the state of Acre) were active against Gram-positive species (Staphylococcus aureus, methicillin-resistant S. aureus, Staphylococcus epidermidis, Bacillus subtilis, and Enterococcus faecalis) with minimum inhibitory concentrations ranging from 31.3-62.5 µg/ml. The oils showed bactericidal activity, decreasing the viability of these Gram-positive bacteria within 3 h. Moderate activity was observed against dermatophyte fungi (Trichophyton rubrum and Microsporum canis). The oils showed no activity against Gram-negative bacteria and yeast. Scannning electron microscopy of S. aureus treated with resin oil from C. martii revealed lysis of the bacteria, causing cellular agglomerates. Transmission electron microscopy revealed disruption and damage to the cell wall, resulting in the release of cytoplasmic compounds, alterations in morphology, and a decrease in cell volume, indicating that copaiba oil may affect the cell wall.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Bálsamos
/
Arthrodermataceae
/
Bactérias Gram-Negativas
/
Bactérias Gram-Positivas
/
Antibacterianos
/
Antifúngicos
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2008
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade Estadual de Londrina/BR
/
Universidade Estadual de Maringá/BR
/
Universidade Federal do Amazonas/BR
/
Universidade Federal do Rio de Janeiro/BR
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