Regional differences in veins wall viscosity, compliance. energetics and damping: analysis of the pressure-diameter relationship during cyclical overloads
Biol. Res
;
41(2): 227-233, 2008. tab, graf
Artigo
em Inglês
| LILACS
| ID: lil-495757
ABSTRACT
Background:
The characterization of the dynamic process of veins walls is essential to understand venous functioning under normal and pathological conditions. However, little work has been done on dynamic venous properties.Aim:
To characterize vein compliance (C), viscosity (η), peak-strain (W St) and dissipated (W D) energy, damping (ξ), and their regional differences in order to evalúate their role in venous functioning during volume-pressure overloads.Methods:
In a mock circulation, pressure (P) and diameter (D) of different veins (anterior cava, jugular and femoral; from 7 sheep), were registered during cyclical volume-pressure pulses. From the P-D relationship, C, W St and ξ (at low and high P-D leveis), η and W D were calculated. Resulls For each vein there were P-dependent differences in biomechanical, energetics, and damping capability. There were regional-differences in C, η), W St and W D (p<0.05), but not in ξ.Conclusión:
The regional-dependent differences in dynamics and energetics, and regional-similitude in damping could be important to ensure venous functioning during acute overloads. The lower C and higher W St and W D found in back-limb veins (femoral), commonly submitted to high volume-pressure loads (i.e. during walking), could be considered relevant to ensure adequate venous system functionality and venous wall protection simultaneously.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Veia Cava Inferior
/
Pressão Sanguínea
/
Volume Sanguíneo
/
Veia Femoral
/
Veias Jugulares
Limite:
Animais
Idioma:
Inglês
Revista:
Biol. Res
Assunto da revista:
Biologia
Ano de publicação:
2008
Tipo de documento:
Artigo
País de afiliação:
Uruguai
Instituição/País de afiliação:
Universidad de la República/UY
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