Perspectivas en la prevención y tratamiento farmacológico de la enfermedad de Alzheimer: [revisión] / Prevention and treatment of Alzheimer disease: [revision]
Rev. méd. Chile
;
137(2): 289-295, feb. 2009.
Artigo
em Espanhol
| LILACS
| ID: lil-516097
ABSTRACT
The pharmacological interventions for Alzheimer disease should be based in its pathogenic mechanisms such as amyloidogenesis, tau hyperphosphorilation, disturbances in neurotransmission and changes in neuronal trophism. Other therapies derive from epidemiological observations, such as antioxidants and anti-inflammatory drugs, estrogens, statins and anti hypertensive drugs. Some life style interventions, such as changes in diet, exercise and brain stimulation could also be beneficial for the prevention of Alzheimer disease. Ongoing research on pathogenic mechanisms promises the discovery of more effective therapies. Healthy life style should always be recommended due to its benefit and lack of untoward effects.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Doença de Alzheimer
/
Estilo de Vida
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
/
Humanos
Idioma:
Espanhol
Revista:
Rev. méd. Chile
Assunto da revista:
Medicina
Ano de publicação:
2009
Tipo de documento:
Artigo
País de afiliação:
Chile
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