A study of iga antibody response to different mycobacterium tuberculosis antigens in the diagnosis and monitoring of pulmonary tuberculosis
Braz. j. infect. dis
;
13(1): 53-58, Feb. 2009. graf, tab
Artigo
em Inglês
| LILACS
| ID: lil-517815
ABSTRACT
We evaluated the performance of the ELISA technique in the detection of IgA antibodies against different Mycobacterium tuberculosis antigenic preparations in serum samples from 49 patients with pulmonary tuberculosis collected before and after the start of specific treatment. The controls consisted of serum samples from healthy patients without any prior contact with the bacteria and serum samples from patients with other pneumopathies. Glycolipid antigen gave the best diagnostic performance, with a sensitivity of 88 percent and specificities varying from 88 to 100 percent in the control groups. These antigens constitute a powerful tool for the diagnosis and monitoring of patients with pulmonary tuberculosis.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Tuberculose Pulmonar
/
Imunoglobulina A
/
Anticorpos Antibacterianos
/
Mycobacterium tuberculosis
/
Antígenos de Bactérias
Tipo de estudo:
Estudo diagnóstico
/
Estudos de avaliação
/
Estudo observacional
/
Estudo prognóstico
Limite:
Adolescente
/
Adulto
/
Idoso
/
Humanos
Idioma:
Inglês
Revista:
Braz. j. infect. dis
Assunto da revista:
Doenças Transmissíveis
Ano de publicação:
2009
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Federal University of Maranhão/BR
/
Federal University of Santa Maria/BR
/
São Paulo Institute of Tropical Medicine/BR
/
University of São Paulo/BR
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