Meta-analysis of the efficacy of non-steroidal anti-inflammatory drugs vs. opioids for SWL using modern electromagnetic lithotripters
Int. braz. j. urol
;
35(3): 293-298, May-June 2009. graf, tab
Artigo
em Inglês
| LILACS
| ID: lil-523154
ABSTRACT
PURPOSE:
Clinical studies produce conflicting results on pain relief for shock wave lithotripsy (SWL). We performed a systematic review and meta-analysis to compare non-steroidal anti-inflammatory drugs (NSAIDs) and opioids in pain relief for SWL powered by an electromagnetic generator. MATERIAL ANDMETHODS:
A search of MEDLINE and EMBASE was performed and all randomized controlled trials comparing NSAIDs and opioids in pain relief for SWL using modern electromagnetic lithotripters were included in the analysis. Data from 3 trials (244 patients) were pooled. The primary outcome measure was adequate analgesia, defined as "if no additional pain relief was used". The difference in the proportion of patients with adequate anesthesia was compared between the NSAIDs and opioids groups as an odds ratio and odds ratio were pooled across the 3 trials with a fixed effects model.RESULTS:
There was no statistically significant difference between using NSAIDs and opioids for pain relief during SWL using modern electromagnetic lithotripters (odds ratio 0.886, 95 percent CI 0.446-1,760, p = 0.730).CONCLUSIONS:
Our analysis shows that in relieving pain during SWL using modern electromagnetic lithotripters NSAIDs are as effective as opioids.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Dor
/
Litotripsia
/
Cálculos Renais
/
Anti-Inflamatórios não Esteroides
/
Analgésicos Opioides
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo de etiologia
/
Revisões Sistemáticas Avaliadas
Limite:
Humanos
Idioma:
Inglês
Revista:
Int. braz. j. urol
Assunto da revista:
Urologia
Ano de publicação:
2009
Tipo de documento:
Artigo
País de afiliação:
Reino Unido
Instituição/País de afiliação:
Harrogate and District NHS Foundation Trust/GB
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