Cistatina C y adiponectina en pacientes diabéticos tipo 2 coronarios y no coronarios / Cystatin C and adiponectin in diabetics with and without coronary artery disease
Rev. méd. Chile
;
137(6): 729-736, jun. 2009. ilus, tab
Artigo
em Espanhol
| LILACS
| ID: lil-524951
ABSTRACT
Background:
Patients with type 2 diabetes have a high incidence of coronary artery disease, which is even higher among those with renal failure. A serum level of cystatin C are used to assess renal function and is a potential cardiovascular risk factor. Adiponectin is an anti-atherogenic factor.Aim:
To measure cystatin C and adiponectin in type 2 diabetic patients with and without coronary artery disease. Material andmethods:
Nine diabetic patients with coronary artery disease aged 76± 10 years, 20 diabetics without coronary artery disease aged 61 ±5 years and 20 non diabetic subjects aged 57±10 years, were studied.Results:
Serum levels of cystatin C (mg/L) were 1.5 (range 0.89-219), 0.81 (range 0.71-1.08) and 0.68 mg/L (range 055-0.75) in diabetics with and without coronary artery disease and controls, respectively (p <0.0001). No differences in adiponectin between groups and no association between cystatin C and adiponectin, were observed. No association between both parameters and body mass index orglycosilated hemoglobin Ale was observed. Cystatin C had a positive correlation with serum creatinine (r =0.57p <0.001).Conclusions:
Diabetics with coronary artery disease have higher levels of cystatin C, that are closely correlated with serum creatinine levels.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Doença da Artéria Coronariana
/
Angiopatias Diabéticas
/
Adiponectina
/
Cistatina C
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Fatores de risco
Limite:
Idoso
/
Humanos
Idioma:
Espanhol
Revista:
Rev. méd. Chile
Assunto da revista:
Medicina
Ano de publicação:
2009
Tipo de documento:
Artigo
País de afiliação:
Chile
Instituição/País de afiliação:
Hospital San Juan de Dios/CL
/
Universidad de Chile/CL
Similares
MEDLINE
...
LILACS
LIS