Association between handling stress in the corral and rabies antibody titers in selenium-supplemented cattle
J. venom. anim. toxins incl. trop. dis
;
15(4): 778-788, 2009. ilus, tab
Artigo
em Inglês
| LILACS
| ID: lil-532760
ABSTRACT
This study determined the correlation between serum cortisol levels and rabies antibody titers in cattle primo-vaccinated against rabies and supplemented with dietary selenium (Se). Sixty Nelore male calves (10 to 12 months old) received daily and individual dietary supplementation with 0, 3.6, 5.4 and 6.4 mg Se (groups Gc, G3.6, G5.4 and G6.4, respectively). The animals were vaccinated against rabies (day 0) and subjected to handling stress in the corral for 120 days. Blood sampling procedures were performed on days 0, 15, 30, 60, 90 and 120. Cortisol levels increased until day 90, but had dropped significantly by day 120 (P < 0.01). Rabies antibody titers on days 30 and 90 were similar among Se-supplemented groups; in the control group, rabies antibodies decreased significantly from day 30 to 60, and 90 to 120. Serum cortisol levels and antibody titers were not correlated in most of the groups or blood sampling days. A positive correlation among these variables was found only in G6.4 on days 60 (R = 0.513; P = 0.05) and 120 (R = 0.644; P = 0.009). In conclusion, repeated handling in the corral stresses cattle, but without compromising rabies humoral immune response.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Raiva
/
Selênio
/
Bovinos
/
Hidrocortisona
/
Anticorpos
Tipo de estudo:
Fatores de risco
Limite:
Animais
Idioma:
Inglês
Revista:
J. venom. anim. toxins incl. trop. dis
Assunto da revista:
Toxicologia
Ano de publicação:
2009
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Butantan Institute/BR
/
São Paulo State University/BR
/
University of Western São Paulo/BR
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