Antiproliferative effect of indomethacin in Aedes albopictus (mosquito) cells
Rev. Ciênc. Méd. Biol. (Impr.)
;
8(1): 14-17, jan.-abr. 2009. graf
Artigo
em Inglês
| LILACS, BBO
| ID: lil-545801
ABSTRACT
Non-steroidal and anti-inflammatory drugs (NSAIDs) are a class of pharmacological agents that are tradicionally used for their anti-cyclooxigenase properties in the treatment of inflammation and other associated diseases. Recently, however, it has been demonstrated that several NSAIDs exhibit antiproliferative effects in various animal models and in vitro experiments. In this paper we demonstrated that treatment of Aedes albopictus cells (mosquito) with indomethacin results in a reduction of normal growth rate. Cells treated with 100 mM indomethacin exhibited a profound time dependent reduction in their proliferation rate over the 96 h test period.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Anti-Inflamatórios não Esteroides
/
Indometacina
/
Aedes
Idioma:
Inglês
Revista:
Rev. Ciênc. Méd. Biol. (Impr.)
Assunto da revista:
Biologia
/
Medicina
Ano de publicação:
2009
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
UFRJ/BR
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