Valores de ferritina sérica em beta talassemia heterozigota: [carta ao editor] / Serum ferritin levels in beta thalassemia carrier: [letter to editor]
Rev. bras. hematol. hemoter
;
32(2): 171-172, 2010. graf, tab
Artigo
em Português
| LILACS
| ID: lil-553477
ABSTRACT
A low iron level, the commonest nutritional deficiency in the world, is a public health problem in developing countries. On the other hand, an excessive amount of iron is toxic, causing several organic dysfunctions, such as diabetes, cirrhosis, endocrinopathies and heart disease. Researchers have reported an association of iron overload with beta-thalassemia. The aim of this paper was to compare the serum ferritin levels of women with the beta-thalassemia trait. The results of serologic tests of 137 women of childbearing age were analyzed; 63 had the beta-thalassemia trait and 74 had Hb AA. In the beta-thalassemia carriers, the median ferritin value was 51.90 ng/mL and in the non-carriers 31.60 ng/mL (p = 0.0052). Levels of less than 20 and above 150 ng/mL were observed in 28 percent and 3 percent of the non-carriers and in 16 percent and 11 percent of the carriers, respectively. With these results it is possible to conclude that women in the reproductive age with the beta-thalassemia trait present higher ferritin levels in the northeastern region of São Paulo State. Further studies are necessary to clarify possible genetic and/or environment factors which interfere in iron absorption.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Talassemia
/
Ferritinas
Limite:
Humanos
Idioma:
Português
Revista:
Rev. bras. hematol. hemoter
Assunto da revista:
Hematologia
Ano de publicação:
2010
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Laboratório Unilab/BR
/
Universidade Estadual Paulista Júlio de Mesquita Filho/BR
/
Universidade Federal de São Carlos/BR
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