Allele frequencies for 12 autosomal short tandem repeat loci in two bolivian populations
Genet. mol. res. (Online)
;
7(1): 271-275, Jan. 2008. tab
Artigo
em Inglês
| LILACS
| ID: lil-553794
ABSTRACT
Two hundred and sixty unrelated subjects who asked for paternity testing at two Bolivian Laboratories in La Paz and Santa Cruz were studied. The loci D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, TH01, TPOX, and CSF1PO were typed from blood samples, amplifying DNA by polymerase chain reactions and electrophoresis. Allele frequencies were estimated by simple counting and the unbiased heterozygosity was calculated. Hardy-Weinberg equilibrium was studied and gene frequencies were compared between the two samples. All loci conformed to the Hardy-Weinberg law and allele frequencies were similar in samples from the two cities. The Bolivian gene frequencies estimated were significantly different from those described for Chile and the United States Hispanic-Americans for most of the loci.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Repetições de Microssatélites
/
Genética Populacional
Limite:
Humanos
País/Região como assunto:
América do Sul
/
Bolívia
Idioma:
Inglês
Revista:
Genet. mol. res. (Online)
Assunto da revista:
Biologia Molecular
/
Genética
Ano de publicação:
2008
Tipo de documento:
Artigo
País de afiliação:
Bolívia
/
Chile
Instituição/País de afiliação:
Genética y Tecnología Ltda/CL
/
Laboratorio de Análisis Clínico Dr. Zuna Ltda/BO
/
Universidad de Chile/CL
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