Síndrome de destrucción vertebral: sistemas de evaluación en su diagnóstico / Vertebral destruction syndrome: diagnostic evaluation systems
Cir. & cir
;
76(3): 205-211, mayo-jun. 2008. ilus, graf, tab
Artigo
em Espanhol
| LILACS
| ID: lil-567107
ABSTRACT
BACKGROUND:
Vertebral Destruction Syndrome (VDS) is a pathology of multiple etiologies causing structural alterations of the spine, producing deformity with neurological and mechanical alterations. In order to study VDS, a diagnostic process is carried out, sometimes with unexpected results. We undertook this study to validate the systematization of a series of studies to arrive at the diagnosis of VDS.METHODS:
We included 105 patients in the study with diagnosis of VDS from January 1998 to December 2005, taking into consideration specificity, sensitivity and predictive value of each integrated study in order to determine its diagnostic value.RESULTS:
The most frequent etiology was Pott's Disease (24 cases) followed by osteomyelitis (20 cases), metastasis (18 cases) and multiple myeloma and plasmacytoma (16 cases each). The higher sensitivity in Pott's Disease was obtained with bone scan and polymerase chain reaction (PCR); for multiple myeloma, computerized axial tomography (CAT) and bone scan; CAT and bone scan for infections; MRI for primary tumors; and MRI and bone scan for secondary tumors.CONCLUSIONS:
To reduce false positives to 2% and to reduce the maximum number of false negatives, studies such as CAT, MRI, bone scan, PCR, ESR, C-reactive protein and determination of alkaline and acid phosphatase must be included in the VDS study protocol. Other studies have very low diagnostic sensitivity and specificity.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Doenças da Coluna Vertebral
Tipo de estudo:
Estudo diagnóstico
/
Guia de Prática Clínica
/
Estudo observacional
/
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
Limite:
Adolescente
/
Idoso
/
Aged80
/
Criança
/
Feminino
/
Humanos
/
Masculino
Idioma:
Espanhol
Revista:
Cir. & cir
Assunto da revista:
Cirurgia Geral
Ano de publicação:
2008
Tipo de documento:
Artigo
País de afiliação:
México
Instituição/País de afiliação:
Secretaría de Salud/MX
/
Universidad Nacional Autónoma de México/MX
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