Predictores clínicos de etapificación en cáncer colorrectal / Clinical predictors of staging in colorectal cancer
Cir. & cir
;
76(4): 311-315, jul.-ago. 2008. tab
Artigo
em Espanhol
| LILACS
| ID: lil-568081
ABSTRACT
OBJECTIVE:
We undertook this study to determine the relationship between clinical symptoms as predictors for staging colorectal cancer (CRC).METHODS:
We performed a cross-sectional study from January 2000 to January 2005 at the [quot ]Hospital Civil Fray Antonio Alcalde.[quot ] All patients with histological diagnosis of CRC were included. Variables analyzed were gender, age, clinical manifestations and location of the tumor, as well as degree of differentiation and time of evolution.RESULTS:
We studied 108 patients with CRC. There were 52 female patients (48.1%) and 56 male patients (51.9%). Twenty five patients were <40 years old (23.15%). Most tumors were well to mildly differentiated adenocarcinomas (88.9%). We observed 37% of proximal tumors with a median evolution time of 11.45 months. Distal tumors were observed in 68 patients with a median evolution time of 9.19 months (p = 0.20). Hemoglobin levels were lower in proximal carcinomas (p = 0.02). Advanced tumors (stages III and IV) corresponded to 82.4% of the cases. The three most common symptoms were rectal bleeding, change in bowel habits and nonspecific abdominal pain. All showed low sensitivity but moderately high specificity (rectal bleeding 89%, change in bowel habits 68%). Combinations of these last two symptoms to predict advanced stage were 55 and 68%.CONCLUSIONS:
The majority of the patients were diagnosed with advanced stages of well-to-mildly differentiated adenocarcinomas. Symptom evaluation as predictors for staging showed a low sensitivity and a moderately high specificity due to a late diagnosis of advanced tumors. We attributed our results to a referral bias, the absence of screening programs and lack of clinical judgment to diagnose CRC at earlier stages.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Neoplasias Colorretais
/
Adenocarcinoma
/
Estadiamento de Neoplasias
Tipo de estudo:
Estudo diagnóstico
/
Estudo de etiologia
/
Estudo de incidência
/
Estudo observacional
/
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
/
Estudo de rastreamento
Limite:
Idoso
/
Aged80
/
Feminino
/
Humanos
/
Masculino
Idioma:
Espanhol
Revista:
Cir. & cir
Assunto da revista:
Cirurgia Geral
Ano de publicação:
2008
Tipo de documento:
Artigo
País de afiliação:
México
Instituição/País de afiliação:
Hospital Civil de Guadalajara Fray Antonio Alcalde/MX
/
Instituto Mexicano del Seguro Social/MX
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