Utilidad de la determinación cualitativa de troponina I y creatinfosfocinasa isoenzima MB en los síndromes isquémicos coronarios agudos / Usefulness of rapid bedside assay of cardiac troponin I and creatine phosphokinase-MB in acute ischemic coronary syndromes
Arch. cardiol. Méx
;
76(1): 37-46, ene.-mar. 2006.
Artigo
em Espanhol
| LILACS
| ID: lil-569529
ABSTRACT
Recently, a rapid bedside assay for quantitative determination of cTI and CPK-MB has been developed that provides a positive or negative result in 10 to 15 minutes allowing for a better therapeutic approach. The objective of our study was to validate the diagnostic usefulness of cardiac troponin I in patients with chest pain. We determined sensitivity, specificity, positive and negative predictive values in 40 patients that arrived to the hospital with chest pain. These patients were assigned to four different groups: Group A: Patients with acute myocardial infarction. Group B: Patients with unstable angina and normal ECG. Group C: Patients with atypical chest pain and normal ECG. Group D: Control. Eighteen (45%) patients were woman and 22 (55%) were men; age 54.1 +/- 26, range 32 to 85 years. In Group A, sensitivity, specificity, positive and negative predictive values for cTI were 95%, for CPK-MB, they were 40, 50, 90, 7.1%. For Group B, cTI: 64, 90, 90, 64%; CPK-MB: 50, 90, 87, 56%. Group C, cTI and CPK MB 25, 95, 50, 86%. Group D, cTI and CPK-MB: 50, 95, 50, 95%. This study suggests that the rapid bedside qualitative test through cardiac troponin I assessment is a test with higher predictive value for early diagnosis of acute myocardial infarction than CPK-MB.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Isquemia Miocárdica
/
Troponina I
/
Creatina Quinase Forma MB
/
Angina Instável
/
Infarto do Miocárdio
Tipo de estudo:
Estudo prognóstico
/
Pesquisa qualitativa
/
Estudo de rastreamento
Limite:
Adulto
/
Idoso
/
Aged80
/
Feminino
/
Humanos
/
Masculino
Idioma:
Espanhol
Revista:
Arch. cardiol. Méx
Assunto da revista:
Cardiologia
Ano de publicação:
2006
Tipo de documento:
Artigo
País de afiliação:
México
Instituição/País de afiliação:
The American British Cowdray Medical Center/MX
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