Cytotoxicity of orthodontic elastics: in vitro investigation with on L929 mouse fibroblasts
Braz. j. oral sci
;
9(3): 366-370, July-Sept. 2010. ilus, tab
Artigo
em Inglês
| LILACS, BBO
| ID: lil-578057
ABSTRACT
Aim: To test the hypothesis that there is no difference in the cytotoxicity among natural latex elastics of different manufacturers using a L929 cell line culture. Methods: Different latex intra oral elastics (I.D. = 5/16", 4.5 oz.) were tested. The sample was divided into 7 groups of 15 elastic seach: Group AO (American Orthodontics), Group GAC (GAC International), Group TP (TP Orthodontics), Group AD (Aditek), Group AB (Abzil), Group MO (Morelli) and Group UN (Uniden).Cytotoxicity assays were performed by using cell culture medium containing L-929 line cells(mouse fibroblast). The cytotoxicity was evaluated by using the dye-uptake test, which wasemployed at two different moments (1 and 24 h). Data were compared by ANOVA and Tukeys test(P < 0.05). Results: The results showed a significant difference (P < 0.05) between all groups and the group CC (cell control) at 1 and 24 h. Groups AD, AB, MO and UN were noticeably more cytotoxic than the groups AO, GAC and TP at 1 h. After 24 h, a significant decrease in cell viability was observed in all groups. Conclusions: Intraoral elastics from American Orthodontics, GACand TP Orthodontics trademarks induced less cell lysis than Aditek, Abzil, Morelli and Uniden trademarks.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Aparelhos Ortodônticos
/
Materiais Dentários
/
Látex
Idioma:
Inglês
Revista:
Braz. j. oral sci
Assunto da revista:
Odontologia
Ano de publicação:
2010
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Federal University of Rio de Janeiro/BR
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